Animal Models of Developmental Neuropathology in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Animal models of schizophrenia: developmental preparation in rats.
Schizophrenia manifests itself primarily with positive symptoms, negative symptoms and cognitive disorders. Animal models of mental diseases seem to be an important tool in understanding key theories related with pathophysiology of the disorder and are used to assess efficacy of new drugs. References describe four basic groups of animal models of schizophrenia, such as: models created by pharma...
متن کاملThe neuropathology of schizophrenia
The distinguished American neurologist, Plum (1972), once called schizophrenia 'the graveyard of neuropathologists'. Certainly the topic of neuropathological change in schizophrenia has been nearly as silent as a tomb for almost three decades. Interest in the neuropathology of schizophrenia was still high in 1952 when leading neuropathologists of the world, meeting at the First International Co...
متن کاملThe neuropathology of schizophrenia.
Insofar as schizophrenia is a neuropsychiatric syndrome involving the brain, neuropathology is a promising, if not essential investigative approach. Although traditional neuropathology has yet to yield a pathognomonic lesion in schizophrenia, there have been no shortages of findings. Unfortunately, many of these findings have not only failed to be pathognomonic, but they have not been consisten...
متن کاملThe neuropathology of schizophrenia
The distinguished American neurologist, Plum (1972), once called schizophrenia 'the graveyard of neuropathologists'. Certainly the topic of neuropathological change in schizophrenia has been nearly as silent as a tomb for almost three decades. Interest in the neuropathology of schizophrenia was still high in 1952 when leading neuropathologists of the world, meeting at the First International Co...
متن کاملImportance of animal models in schizophrenia research.
OBJECTIVE This review aims to summarize the importance of animal models for research on psychiatric illnesses, particularly schizophrenia. METHOD AND RESULTS Several aspects of animal models are addressed, including animal experimentation ethics and theoretical considerations of different aspects of validity of animal models. A more specific discussion is included on two of the most widely us...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2017
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sbx116